9dj9

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m (Protected "9dj9" [edit=sysop:move=sysop])
Current revision (05:19, 25 September 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9dj9 is ON HOLD
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==HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in distinct apo form==
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<StructureSection load='9dj9' size='340' side='right'caption='[[9dj9]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
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Authors: Keedy, D.A., Lemberikman, A.M., Isiorho, E.A., Aleshin, A.E., Wu, J., Lambert, L.J., Cosford, N.D.P., Tautz, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9dj9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DJ9 FirstGlance]. <br>
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Description: HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in distinct apo form
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.924&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dj9 OCA], [https://pdbe.org/9dj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dj9 RCSB], [https://www.ebi.ac.uk/pdbsum/9dj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dj9 ProSAT]</span></td></tr>
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[[Category: Wu, J]]
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</table>
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[[Category: Isiorho, E.A]]
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== Function ==
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[[Category: Lambert, L.J]]
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[https://www.uniprot.org/uniprot/DUS3_HUMAN DUS3_HUMAN] Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.<ref>PMID:10224087</ref> <ref>PMID:11863439</ref>
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[[Category: Cosford, N.D.P]]
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== References ==
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[[Category: Keedy, D.A]]
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<references/>
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[[Category: Aleshin, A.E]]
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__TOC__
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[[Category: Tautz, L]]
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</StructureSection>
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[[Category: Lemberikman, A.M]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Aleshin AE]]
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[[Category: Cosford NDP]]
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[[Category: Isiorho EA]]
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[[Category: Keedy DA]]
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[[Category: Lambert LJ]]
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[[Category: Lemberikman AM]]
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[[Category: Tautz L]]
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[[Category: Wu J]]

Current revision

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in distinct apo form

PDB ID 9dj9

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OCA

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