9gkf

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Current revision (10:24, 3 September 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9gkf is ON HOLD until Paper Publication
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==Amyloid Fibril of Heterogeneous nuclear ribonucleoprotein A1A induced by RNA binding==
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<StructureSection load='9gkf' size='340' side='right'caption='[[9gkf]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
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Authors: Frey, L., Riek, R.P., Arosio, P., Morelli, C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9gkf]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GKF FirstGlance]. <br>
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Description: Amyloid Fibril of Heterogeneous nuclear ribonucleoprotein A1A induced by RNA binding
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gkf OCA], [https://pdbe.org/9gkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gkf RCSB], [https://www.ebi.ac.uk/pdbsum/9gkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gkf ProSAT]</span></td></tr>
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[[Category: Arosio, P]]
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</table>
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[[Category: Riek, R.P]]
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== Disease ==
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[[Category: Morelli, C]]
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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[[Category: Frey, L]]
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== Function ==
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arosio P]]
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[[Category: Frey L]]
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[[Category: Morelli C]]
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[[Category: Riek RP]]

Current revision

Amyloid Fibril of Heterogeneous nuclear ribonucleoprotein A1A induced by RNA binding

PDB ID 9gkf

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