1tif

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{{STRUCTURE_1tif| PDB=1tif | SCENE= }}
{{STRUCTURE_1tif| PDB=1tif | SCENE= }}
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'''TRANSLATION INITIATION FACTOR 3 N-TERMINAL DOMAIN'''
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===TRANSLATION INITIATION FACTOR 3 N-TERMINAL DOMAIN===
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==Overview==
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The structures of the two domains of translational initiation factor IF3 from Bacillus stearothermophilus have been solved by X-ray crystallography using single wavelength anomalous scattering and multiwavelength anomalous diffraction. Each of the two domains has an alpha/beta topology, with an exposed beta-sheet that is reminiscent of several ribosomal and other RNA binding proteins. An alpha-helix that protrudes out from the body of the N-terminal domain towards the C-terminal domain suggests that IF3 consists of two RNA binding domains connected by an alpha-helix and that it may bridge two regions of the ribosome. This represents the first high resolution structural information on a translational initiation factor.
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The line below this paragraph, {{ABSTRACT_PUBMED_7664745}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7664745 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7664745}}
==About this Structure==
==About this Structure==
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[[Category: Shu, F.]]
[[Category: Shu, F.]]
[[Category: If3 n-terminal domain]]
[[Category: If3 n-terminal domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:59:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:51:22 2008''

Revision as of 13:51, 27 July 2008

Image:1tif.png

Template:STRUCTURE 1tif

TRANSLATION INITIATION FACTOR 3 N-TERMINAL DOMAIN

Template:ABSTRACT PUBMED 7664745

About this Structure

1TIF is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix., Biou V, Shu F, Ramakrishnan V, EMBO J. 1995 Aug 15;14(16):4056-64. PMID:7664745

Page seeded by OCA on Sun Jul 27 16:51:22 2008

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