9dkd

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Current revision (08:18, 4 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9dkd is ON HOLD until Paper Publication
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==CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis1.==
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<StructureSection load='9dkd' size='340' side='right'caption='[[9dkd]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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Authors: Kendrick, A.A., Leschziner, A.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9dkd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DKD FirstGlance]. <br>
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Description: CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis1.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Kendrick, A.A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dkd OCA], [https://pdbe.org/9dkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dkd RCSB], [https://www.ebi.ac.uk/pdbsum/9dkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dkd ProSAT]</span></td></tr>
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[[Category: Leschziner, A.E]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DYHC_YEAST DYHC_YEAST] Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle.<ref>PMID:15642746</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Kendrick AA]]
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[[Category: Leschziner AE]]

Current revision

CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis1.

PDB ID 9dkd

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