9jqy
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural Insights into Selective Antagonism of TG6-129 and EP4 Prostaglandin Receptor== | |
| - | + | <StructureSection load='9jqy' size='340' side='right'caption='[[9jqy]], [[Resolution|resolution]] 2.92Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9jqy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JQY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.92Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EC5:~{N}-[[4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl]carbamothioyl]-3-(4-fluorophenyl)propanamide'>A1EC5</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jqy OCA], [https://pdbe.org/9jqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jqy RCSB], [https://www.ebi.ac.uk/pdbsum/9jqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jqy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PE2R4_HUMAN PE2R4_HUMAN] Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Wu CR]] | ||
| + | [[Category: Wu YL]] | ||
| + | [[Category: Xu EH]] | ||
| + | [[Category: Xu JY]] | ||
| + | [[Category: Zhang H]] | ||
Current revision
Structural Insights into Selective Antagonism of TG6-129 and EP4 Prostaglandin Receptor
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Categories: Homo sapiens | Large Structures | Mus musculus | Synthetic construct | Wu CR | Wu YL | Xu EH | Xu JY | Zhang H
