We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1uco

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1uco.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1uco.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1uco| PDB=1uco | SCENE= }}
{{STRUCTURE_1uco| PDB=1uco | SCENE= }}
-
'''HEN EGG-WHITE LYSOZYME, LOW HUMIDITY FORM'''
+
===HEN EGG-WHITE LYSOZYME, LOW HUMIDITY FORM===
-
==Overview==
+
<!--
-
The atomic models of native monoclinic lysozyme obtained by refinement at Bangalore and elsewhere [Young, Dewan, Nave &amp; Tilton (1993). J. Appl. Cryst. 26, 309-319] differed significantly in the flexible regions of the protein molecule. The two models were reconciled starting from regions where they were in reasonable agreement to produce an improved model which yielded an R value of 0.169 for 12 816 observed reflections in the 10-2 A resolution range. The reconciled model was compared with the structure of the 88% relative humidity form obtained through a water-mediated transformation [Madhusudan, Kodandapani &amp; Vijayan (1993). Acta Cryst. D49, 234-245]. Parts of the flexible regions of the molecule register significant movements during the transformation. The changes resulting from the transformation from the native to the low-humidity forms are pronounced in many of the side chains in the active-site region, thus indicating the relationship between hydration, mobility and enzyme action. The fact that the overall changes in molecular geometry resulting from water-mediated transformation are similar to those which occur during enzyme action, further emphasizes this relationship.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15299565}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15299565 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15299565}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: O-glycosyl]]
[[Category: O-glycosyl]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:02:41 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:41:26 2008''

Revision as of 20:41, 27 July 2008

Image:1uco.png

Template:STRUCTURE 1uco

HEN EGG-WHITE LYSOZYME, LOW HUMIDITY FORM

Template:ABSTRACT PUBMED 15299565

About this Structure

1UCO is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

An X-ray analysis of native monoclinic lysozyme. A case study on the reliability of refined protein structures and a comparison with the low-humidity form in relation to mobility and enzyme action., Nagendra HG, Sudarsanakumar C, Vijayan M, Acta Crystallogr D Biol Crystallogr. 1996 Nov 1;52(Pt 6):1067-74. PMID:15299565

Page seeded by OCA on Sun Jul 27 23:41:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1uco"
Personal tools