1ul3

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{{STRUCTURE_1ul3| PDB=1ul3 | SCENE= }}
{{STRUCTURE_1ul3| PDB=1ul3 | SCENE= }}
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'''Crystal Structure of PII from Synechocystis sp. PCC 6803'''
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===Crystal Structure of PII from Synechocystis sp. PCC 6803===
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==Overview==
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The PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803 have been crystallized and high-resolution structures have been obtained using X-ray crystallography. The core of these new structures is similar to that of the PII proteins from Escherichia coli, although the structures of the T- and C-loops differ. The T-loop of the Synechococcus protein is ordered, but appears to be stabilized by crystal contacts. The same loop in the Synechocystis protein is disordered. The C-terminus of the Synechocystis protein is stabilized by hydrogen bonding to the same region of a crystallographically related molecule. The same terminus in the Synechococcus protein is stabilized by coordination with a metal ion. These observations are consistent with the idea that both the T-loop and the C-terminus of PII proteins are flexible in solution and that this flexibility may be important for receptor recognition. Sequence comparisons are used to identify regions of the sequence unique to the cyanobacteria.
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{{ABSTRACT_PUBMED_14646076}}
==About this Structure==
==About this Structure==
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[[Category: Cyanobacteria]]
[[Category: Cyanobacteria]]
[[Category: Nitrogen regulation]]
[[Category: Nitrogen regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:22:27 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:55:06 2008''

Revision as of 23:55, 27 July 2008

Image:1ul3.png

Template:STRUCTURE 1ul3

Crystal Structure of PII from Synechocystis sp. PCC 6803

Template:ABSTRACT PUBMED 14646076

About this Structure

1UL3 is a Single protein structure of sequence from Synechocystis sp.. Full crystallographic information is available from OCA.

Reference

The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803., Xu Y, Carr PD, Clancy P, Garcia-Dominguez M, Forchhammer K, Florencio F, Vasudevan SG, Tandeau de Marsac N, Ollis DL, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2183-90. Epub 2003, Nov 27. PMID:14646076

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