Drug and peptide transport in humans
From Proteopedia
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<StructureSection load='' size='350' side='right' caption='' scene='10/1066775/Chimerax-morph-pdb/2'> | <StructureSection load='' size='350' side='right' caption='' scene='10/1066775/Chimerax-morph-pdb/2'> | ||
| + | ==Peptide Transporter Function & Structure== | ||
| + | Human peptide transporter 1 ('''PepT1''') plays a crucual role in nutrition, transporting peptides from digested protein into intestinal cells.<ref name="kl">PMID: 34730990</ref> It is also crucial in uptake of orally delivered drugs. | ||
<scene name='10/1066775/7pmx/1'>7pmx cartoon</scene> | <scene name='10/1066775/7pmx/1'>7pmx cartoon</scene> | ||
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<scene name='10/1066775/Pacupp_7pmy_xf_s/2'>inward-facing containing dipeptide</scene> | <scene name='10/1066775/Pacupp_7pmy_xf_s/2'>inward-facing containing dipeptide</scene> | ||
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| + | outward facing morph spacefilled showing dipeptide visible/hidden | ||
</StructureSection> | </StructureSection> | ||
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| + | ==References and Notes== | ||
| + | <references /> | ||
Revision as of 00:50, 4 December 2024
This page is under construction. This notice will be removed when it is ready. Eric Martz 01:56, 3 December 2024 (UTC) |
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References and Notes
- ↑ Killer M, Wald J, Pieprzyk J, Marlovits TC, Low C. Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv. 2021 Nov 5;7(45):eabk3259. doi: 10.1126/sciadv.abk3259. Epub 2021 Nov 3. PMID:34730990 doi:http://dx.doi.org/10.1126/sciadv.abk3259
