1y8j
From Proteopedia
(New page: 200px<br /> <applet load="1y8j" size="450" color="white" frame="true" align="right" spinBox="true" caption="1y8j, resolution 2.25Å" /> '''Crystal Structure o...) |
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| - | [[Image:1y8j.gif|left|200px]]<br /> | + | [[Image:1y8j.gif|left|200px]]<br /><applet load="1y8j" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1y8j" size=" | + | |
caption="1y8j, resolution 2.25Å" /> | caption="1y8j, resolution 2.25Å" /> | ||
'''Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor'''<br /> | '''Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1Y8J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with NAG, ZN, ACT and STS as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Neprilysin Neprilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.11 3.4.24.11] Full crystallographic information is available from [http:// | + | 1Y8J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=STS:'>STS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Neprilysin Neprilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.11 3.4.24.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y8J OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Neprilysin]] | [[Category: Neprilysin]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Aebi, J | + | [[Category: Aebi, J D.]] |
[[Category: Blum-Kaelin, D.]] | [[Category: Blum-Kaelin, D.]] | ||
| - | [[Category: Bohm, H | + | [[Category: Bohm, H J.]] |
| - | [[Category: Dale, G | + | [[Category: Dale, G E.]] |
[[Category: Diederich, F.]] | [[Category: Diederich, F.]] | ||
[[Category: Frank, B.]] | [[Category: Frank, B.]] | ||
[[Category: Oefner, C.]] | [[Category: Oefner, C.]] | ||
[[Category: Sahli, S.]] | [[Category: Sahli, S.]] | ||
| - | [[Category: Schweizer, W | + | [[Category: Schweizer, W B.]] |
[[Category: ACT]] | [[Category: ACT]] | ||
[[Category: NAG]] | [[Category: NAG]] | ||
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[[Category: lt1_6]] | [[Category: lt1_6]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:02:47 2008'' |
Revision as of 14:02, 21 February 2008
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Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor
Disease
Known diseases associated with this structure: Membranous glomerulonephritis, antenatal OMIM:[120520], Neutral endopeptidase deficiency OMIM:[120520], Schizophrenia, susceptibility to OMIM:[607265]
About this Structure
1Y8J is a Single protein structure of sequence from Homo sapiens with , , and as ligands. Active as Neprilysin, with EC number 3.4.24.11 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 16:02:47 2008
Categories: Homo sapiens | Neprilysin | Single protein | Aebi, J D. | Blum-Kaelin, D. | Bohm, H J. | Dale, G E. | Diederich, F. | Frank, B. | Oefner, C. | Sahli, S. | Schweizer, W B. | ACT | NAG | STS | ZN | Lt1 6
