9kx8
From Proteopedia
(Difference between revisions)
m (Protected "9kx8" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mistletoe Lectin I from Viscum album complexed with epimer form of lactose== | |
| - | + | <StructureSection load='9kx8' size='340' side='right'caption='[[9kx8]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9kx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Viscum_album Viscum album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KX8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZCD:alpha-D-idopyranose'>ZCD</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kx8 OCA], [https://pdbe.org/9kx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kx8 RCSB], [https://www.ebi.ac.uk/pdbsum/9kx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kx8 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Alves Franca | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ML1_VISAL ML1_VISAL] The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity). Inhibits growth of the human tumor cell line Molt4.<ref>PMID:15182350</ref> <ref>PMID:15001393</ref> <ref>PMID:1450445</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Viscum album]] | ||
| + | [[Category: Akrem A]] | ||
| + | [[Category: Alves Franca B]] | ||
| + | [[Category: Betzel C]] | ||
| + | [[Category: Brognaro H]] | ||
| + | [[Category: Khaliq B]] | ||
| + | [[Category: Mehmood S]] | ||
| + | [[Category: Rajaiah Prabhu P]] | ||
| + | [[Category: Saeed A]] | ||
Current revision
Mistletoe Lectin I from Viscum album complexed with epimer form of lactose
| |||||||||||
