9kh2

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Current revision (06:22, 26 November 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9kh2 is ON HOLD until Paper Publication
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==Crystal structure of the first three zinc finger domains of ZBTB20 in complex with DNA==
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<StructureSection load='9kh2' size='340' side='right'caption='[[9kh2]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
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Authors: Chen, X., Luo, Z., Song, Y., Xu, S., Wu, J., Duan, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9kh2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KH2 FirstGlance]. <br>
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Description: Crystal structure of the first three zinc finger domains of ZBTB20 in complex with DNA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Duan, B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kh2 OCA], [https://pdbe.org/9kh2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kh2 RCSB], [https://www.ebi.ac.uk/pdbsum/9kh2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kh2 ProSAT]</span></td></tr>
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[[Category: Xu, S]]
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</table>
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[[Category: Luo, Z]]
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== Disease ==
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[[Category: Wu, J]]
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[https://www.uniprot.org/uniprot/ZBT20_HUMAN ZBT20_HUMAN] Intellectual disability-cataracts-calcified pinnae-myopathy syndrome. The disease is caused by variants affecting the gene represented in this entry.
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[[Category: Song, Y]]
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== Function ==
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[[Category: Chen, X]]
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[https://www.uniprot.org/uniprot/ZBT20_HUMAN ZBT20_HUMAN] May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (PubMed:11352661). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).[UniProtKB:Q8K0L9]<ref>PMID:11352661</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Chen X]]
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[[Category: Duan B]]
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[[Category: Luo Z]]
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[[Category: Song Y]]
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[[Category: Wu J]]
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[[Category: Xu S]]

Current revision

Crystal structure of the first three zinc finger domains of ZBTB20 in complex with DNA

PDB ID 9kh2

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OCA

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