8xna

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Current revision (09:03, 2 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8xna is ON HOLD until 2026-03-29
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==Crystal structure of serine hydroxymethyltransferase 2==
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<StructureSection load='8xna' size='340' side='right'caption='[[8xna]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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Authors: Fan, S., Lv, R., Wang, C., Tang, M., Wei, X., Jin, Y., Yang, Z.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8xna]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XNA FirstGlance]. <br>
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Description: Crystal structure of serine hydroxymethyltransferase 2
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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[[Category: Fan, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xna OCA], [https://pdbe.org/8xna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xna RCSB], [https://www.ebi.ac.uk/pdbsum/8xna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xna ProSAT]</span></td></tr>
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[[Category: Lv, R]]
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</table>
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[[Category: Tang, M]]
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== Function ==
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[[Category: Wei, X]]
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[https://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref>
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[[Category: Jin, Y]]
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== References ==
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[[Category: Yang, Z]]
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<references/>
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[[Category: Wang, C]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Fan S]]
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[[Category: Jin Y]]
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[[Category: Lv R]]
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[[Category: Tang M]]
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[[Category: Wang C]]
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[[Category: Wei X]]
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[[Category: Yang Z]]

Current revision

Crystal structure of serine hydroxymethyltransferase 2

PDB ID 8xna

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