8y0n

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Current revision (18:56, 26 February 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8y0n is ON HOLD until 2026-07-22
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==Structure of CXCR3 in complex with VUF11418 and Go (Full map)==
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<StructureSection load='8y0n' size='340' side='right'caption='[[8y0n]], [[Resolution|resolution]] 3.07&Aring;' scene=''>
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Authors: Sano, F.K., Saha, S., Sharma, S., Ganguly, M., Shihoya, W., Nureki, O., Shukla, A.K., Banerjee, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8y0n]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y0N FirstGlance]. <br>
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Description: Structure of CXCR3 in complex with VUF11418 and Go (Full map)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.07&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1LW2:[(1~{R},5~{S})-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-[[4-(2-iodanylphenyl)phenyl]methyl]-dimethyl-azanium'>A1LW2</scene></td></tr>
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[[Category: Nureki, O]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y0n OCA], [https://pdbe.org/8y0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y0n RCSB], [https://www.ebi.ac.uk/pdbsum/8y0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y0n ProSAT]</span></td></tr>
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[[Category: Ganguly, M]]
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</table>
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[[Category: Saha, S]]
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== Disease ==
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[[Category: Banerjee, R]]
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[https://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Sano, F.K]]
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== Function ==
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[[Category: Shihoya, W]]
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[https://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.
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[[Category: Shukla, A.K]]
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__TOC__
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[[Category: Sharma, S]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Banerjee R]]
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[[Category: Ganguly M]]
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[[Category: Nureki O]]
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[[Category: Saha S]]
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[[Category: Sano FK]]
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[[Category: Sharma S]]
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[[Category: Shihoya W]]
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[[Category: Shukla AK]]

Current revision

Structure of CXCR3 in complex with VUF11418 and Go (Full map)

PDB ID 8y0n

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OCA

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