9ehs
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602== | |
| - | + | <StructureSection load='9ehs' size='340' side='right'caption='[[9ehs]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ehs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EHS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1BII:4-({3-[(5S)-8-methoxy-2,4-dioxo-3-propyl-3,4-dihydropyrido[2,1-f]purin-1(2H)-yl]propyl}carbamoyl)benzene-1-sulfonyl+fluoride'>A1BII</scene></td></tr> |
| - | [[Category: Glukhova | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ehs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ehs OCA], [https://pdbe.org/9ehs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ehs RCSB], [https://www.ebi.ac.uk/pdbsum/9ehs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ehs ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Thal | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/AA3R_HUMAN AA3R_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase (PubMed:8234299).<ref>PMID:8234299</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Glukhova A]] | ||
| + | [[Category: Mobbs JI]] | ||
| + | [[Category: Thal DM]] | ||
| + | [[Category: Zhang L]] | ||
Current revision
Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602
| |||||||||||
