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9l0c
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==structure of MCT2-embigin-AR-C155858 complex== | |
| - | + | <StructureSection load='9l0c' size='340' side='right'caption='[[9l0c]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9l0c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L0C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EH2:6-[(3,5-dimethyl-1~{H}-pyrazol-4-yl)methyl]-3-methyl-1-(2-methylpropyl)-5-[[(4~{S})-4-oxidanyl-1,2-oxazolidin-2-yl]carbonyl]thieno[2,3-d]pyrimidine-2,4-dione'>A1EH2</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l0c OCA], [https://pdbe.org/9l0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l0c RCSB], [https://www.ebi.ac.uk/pdbsum/9l0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l0c ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EMB_HUMAN EMB_HUMAN] Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1, SLC16A6 and SLC16A7 to the cell membrane (By similarity).[UniProtKB:O88775] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Xu B]] | ||
Current revision
structure of MCT2-embigin-AR-C155858 complex
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