9kqs
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of WDR5 in complex with peptide MRTEPRPPAP of EMBOW== | |
| - | + | <StructureSection load='9kqs' size='340' side='right'caption='[[9kqs]], [[Resolution|resolution]] 1.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9kqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KQS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kqs OCA], [https://pdbe.org/9kqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kqs RCSB], [https://www.ebi.ac.uk/pdbsum/9kqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kqs ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OSCRI_HUMAN OSCRI_HUMAN] Represses translation of the downstream SCRIB protein (PubMed:34535749). Translation of oSCRIB hinders SCRIB translation but does not completely abolish it, probably due to leaky scanning which allows the ribosome to bypass the weaker oSCRIB start codon and initiate translation at the stronger SCRIB start codon (PubMed:34535749).<ref>PMID:34535749</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen M-X]] | ||
| + | [[Category: Min J-R]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Crystal structure of WDR5 in complex with peptide MRTEPRPPAP of EMBOW
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