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9ll1

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Current revision (06:57, 31 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9ll1 is ON HOLD until Paper Publication
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==Cryo-EM structure of G6PT1 in complex with Chlorogenic acid==
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<StructureSection load='9ll1' size='340' side='right'caption='[[9ll1]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9ll1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LL1 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EG7:(1~{S},3~{R},4~{R},5~{R})-3-[(~{E})-3-[3,4-bis(oxidanyl)phenyl]prop-2-enoyl]oxy-1,4,5-tris(oxidanyl)cyclohexane-1-carboxylic+acid'>A1EG7</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ll1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ll1 OCA], [https://pdbe.org/9ll1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ll1 RCSB], [https://www.ebi.ac.uk/pdbsum/9ll1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ll1 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/G6PT1_HUMAN G6PT1_HUMAN] Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/G6PT1_HUMAN G6PT1_HUMAN] Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction (PubMed:33964207). Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.<ref>PMID:10026167</ref> <ref>PMID:21949678</ref> <ref>PMID:33964207</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen Q]]
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[[Category: Zhao Y]]

Current revision

Cryo-EM structure of G6PT1 in complex with Chlorogenic acid

PDB ID 9ll1

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