9mw5

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Current revision (08:23, 13 August 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9mw5 is ON HOLD until Paper Publication
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==D1 Herpes Virus Simplex Neutralizing Nanobody Bound to HSV Glycoprotein gB==
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<StructureSection load='9mw5' size='340' side='right'caption='[[9mw5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9mw5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MW5 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mw5 OCA], [https://pdbe.org/9mw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mw5 RCSB], [https://www.ebi.ac.uk/pdbsum/9mw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mw5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GB_HHV2H GB_HHV2H] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Abernathy E]]
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[[Category: Hung M]]
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[[Category: Lee CV]]
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[[Category: Viadiu H]]
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[[Category: Xing W]]
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[[Category: Yu X]]
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[[Category: Yu Y]]

Current revision

D1 Herpes Virus Simplex Neutralizing Nanobody Bound to HSV Glycoprotein gB

PDB ID 9mw5

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