9mny
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human MPC with pyruvate== | |
| - | + | <StructureSection load='9mny' size='340' side='right'caption='[[9mny]], [[Resolution|resolution]] 2.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9mny]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MNY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MNY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mny OCA], [https://pdbe.org/9mny PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mny RCSB], [https://www.ebi.ac.uk/pdbsum/9mny PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mny ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/MPC1_HUMAN MPC1_HUMAN] Mitochondrial pyruvate carrier deficiency. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MPC1_HUMAN MPC1_HUMAN] Mediates the uptake of pyruvate into mitochondria.<ref>PMID:22628558</ref> <ref>PMID:26253029</ref> <ref>PMID:27317664</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Feng L]] | ||
| + | [[Category: He Z]] | ||
| + | [[Category: Zhang J]] | ||
Current revision
Cryo-EM structure of human MPC with pyruvate
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