9ga4
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==MtUvrA2UvrB2 bound to damaged oligonucleotide== | |
| - | + | <StructureSection load='9ga4' size='340' side='right'caption='[[9ga4]], [[Resolution|resolution]] 3.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ga4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GA4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ga4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ga4 OCA], [https://pdbe.org/9ga4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ga4 RCSB], [https://www.ebi.ac.uk/pdbsum/9ga4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ga4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UVRA_MYCTU UVRA_MYCTU] The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. Alone it slightly inhibits RecA-mediated DNA strand exchange, in concert with UvrD1 greatly inhibits RecA-mediated DNA strand exchange.<ref>PMID:20455546</ref> <ref>PMID:22467787</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Bolognesi M]] | ||
| + | [[Category: Capelli R]] | ||
| + | [[Category: Chaves-Sanjuan A]] | ||
| + | [[Category: Ferrara G]] | ||
| + | [[Category: Genta M]] | ||
| + | [[Category: Jeruzalmi D]] | ||
| + | [[Category: Miggiano R]] | ||
| + | [[Category: Rizzi M]] | ||
| + | [[Category: Rossi F]] | ||
Current revision
MtUvrA2UvrB2 bound to damaged oligonucleotide
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