9lkr

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Current revision (07:40, 19 November 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9lkr is ON HOLD until Paper Publication
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==Crystal Structure of the bromodomain of human BRD9 in complex with the inhibitor Y22076==
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<StructureSection load='9lkr' size='340' side='right'caption='[[9lkr]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
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Authors: Chen, Z., Zhang, C., Xu, H., Wu, X., Zhang, Y., Xu, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9lkr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LKR FirstGlance]. <br>
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Description: Crystal Structure of the bromodomain of human BRD9 in complex with the inhibitor Y22076
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EKN:1-[1-[4-(imidazol-1-ylmethyl)-3,5-dimethoxy-phenyl]indolizin-3-yl]ethanone'>A1EKN</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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[[Category: Chen, Z]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lkr OCA], [https://pdbe.org/9lkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lkr RCSB], [https://www.ebi.ac.uk/pdbsum/9lkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lkr ProSAT]</span></td></tr>
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[[Category: Xu, Y]]
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</table>
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[[Category: Zhang, C]]
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== Function ==
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[[Category: Zhang, Y]]
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[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription.
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[[Category: Wu, X]]
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__TOC__
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[[Category: Xu, H]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen Z]]
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[[Category: Wu X]]
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[[Category: Xu H]]
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[[Category: Xu Y]]
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[[Category: Zhang C]]
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[[Category: Zhang Y]]

Current revision

Crystal Structure of the bromodomain of human BRD9 in complex with the inhibitor Y22076

PDB ID 9lkr

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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