9l5x

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Current revision (07:12, 15 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9l5x is ON HOLD until 2026-12-23
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==Crystal structure of Klebsiella pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabI) in complex with Triclosan==
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<StructureSection load='9l5x' size='340' side='right'caption='[[9l5x]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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Authors: Biswas, S., Patra, A., Kushwaha, G.S., Suar, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9l5x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_12-3578 Klebsiella pneumoniae subsp. pneumoniae 12-3578]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L5X FirstGlance]. <br>
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Description: Crystal structure of Klebsiella pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabI) in complex with Triclosan
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr>
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[[Category: Patra, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l5x OCA], [https://pdbe.org/9l5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l5x RCSB], [https://www.ebi.ac.uk/pdbsum/9l5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l5x ProSAT]</span></td></tr>
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[[Category: Suar, M]]
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</table>
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[[Category: Kushwaha, G.S]]
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== Function ==
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[[Category: Biswas, S]]
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[https://www.uniprot.org/uniprot/A0A1Y0Q1M7_KLEPN A0A1Y0Q1M7_KLEPN] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.[ARBA:ARBA00025542]
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__TOC__
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</StructureSection>
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[[Category: Klebsiella pneumoniae subsp. pneumoniae 12-3578]]
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[[Category: Large Structures]]
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[[Category: Biswas S]]
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[[Category: Kushwaha GS]]
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[[Category: Patra A]]
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[[Category: Suar M]]

Current revision

Crystal structure of Klebsiella pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabI) in complex with Triclosan

PDB ID 9l5x

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