User:Matthew Pereira/Sandbox 1

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=SARS-CoV-2 minibinders=
=SARS-CoV-2 minibinders=
<StructureSection load='7jzl' size='350' frame='true' side='right' caption='SARS-CoV-2 Spike Protein Bound to Minibinders (PDB 7jzl)' scene=''>
<StructureSection load='7jzl' size='350' frame='true' side='right' caption='SARS-CoV-2 Spike Protein Bound to Minibinders (PDB 7jzl)' scene=''>
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This is a default text for your page '''Matthew Pereira/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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This is test text to fill space.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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==Introduction==
==Introduction==
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== Disease/Relevance ==
 
[https://en.wikipedia.org/wiki/COVID-19 COVID-19]
[https://en.wikipedia.org/wiki/COVID-19 COVID-19]
==Function==
==Function==
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[[Image:Spike monomer bound to ACE2.png|400 px|left|thumb|Bad Image to be Replaced]] <ref name="Longxing">PMID:32907861</ref>
[[Image:Spike monomer bound to ACE2.png|400 px|left|thumb|Bad Image to be Replaced]] <ref name="Longxing">PMID:32907861</ref>
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==Binding Site==
==Binding Site==
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<scene name='10/1075220/Leu44/1'>leu44</scene>
<scene name='10/1075220/Leu44/1'>leu44</scene>
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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This is a test scene of a random residue of the minibinder with an unrelated citation<ref name="Ransey">PMID:28504306</ref>.
</StructureSection>
</StructureSection>
== References ==
== References ==
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<ref name="Ransey">PMID:28504306</ref>
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<references/>
<references/>
==Student Contributors==
==Student Contributors==
Matt Pereira, Giavanna Yowel, and Shae Bailey
Matt Pereira, Giavanna Yowel, and Shae Bailey

Revision as of 19:43, 18 March 2025

SARS-CoV-2 minibinders

SARS-CoV-2 Spike Protein Bound to Minibinders (PDB 7jzl)

Drag the structure with the mouse to rotate

References

  1. ↑ Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls AC, Park YJ, Strauch EM, Stewart L, Diamond MS, Veesler D, Baker D. De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science. 2020 Oct 23;370(6515):426-431. PMID:32907861 doi:10.1126/science.abd9909
  2. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

Matt Pereira, Giavanna Yowel, and Shae Bailey

Proteopedia Page Contributors and Editors (what is this?)

Matthew Pereira

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