9hfs
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer with dCTP bound in the active site== | |
| - | + | <StructureSection load='9hfs' size='340' side='right'caption='[[9hfs]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9hfs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HFS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCP:2-DEOXYCYTIDINE-5-TRIPHOSPHATE'>DCP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hfs OCA], [https://pdbe.org/9hfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hfs RCSB], [https://www.ebi.ac.uk/pdbsum/9hfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hfs ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CDAC1_HUMAN CDAC1_HUMAN] Catalyzes the deamination of cytidine and deoxycytidine into uridine and deoxyuridine, respectively (PubMed:26945630). May play an important role in testicular development and spermatogenesis (PubMed:16955368).<ref>PMID:16955368</ref> <ref>PMID:26945630</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bochtler M]] | ||
| + | [[Category: Czarnocki-Cieciura M]] | ||
| + | [[Category: Kanai T]] | ||
| + | [[Category: Lountos G]] | ||
| + | [[Category: Rathore I]] | ||
| + | [[Category: Skowronek K]] | ||
| + | [[Category: Slyvka A]] | ||
| + | [[Category: Wang Z]] | ||
| + | [[Category: Wlodawer A]] | ||
| + | [[Category: Yang R]] | ||
Current revision
Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer with dCTP bound in the active site
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Categories: Homo sapiens | Large Structures | Bochtler M | Czarnocki-Cieciura M | Kanai T | Lountos G | Rathore I | Skowronek K | Slyvka A | Wang Z | Wlodawer A | Yang R
