User:Elizabeth Yowell/SandboxGiavanna
From Proteopedia
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| - | =SARS CoV-2 Protein Inhibitors (AHB2 and LCB1/LCB3)= | + | <scene name='10/1076049/Antibody/1'>Text To Be Displayed</scene>=SARS CoV-2 Protein Inhibitors (AHB2 and LCB1/LCB3)= |
<StructureSection load='7UHB' size='350' frame= 'true' side= 'right' caption='AHB2 Inhibitor 7UHB' scene ='10/1075216/Practice/1'> | <StructureSection load='7UHB' size='350' frame= 'true' side= 'right' caption='AHB2 Inhibitor 7UHB' scene ='10/1075216/Practice/1'> | ||
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The enzyme angiotensin converting enzyme 2 (ACE2) is attached to our cell membranes bound to a receptor binding domain (RBD) <ref name="Borkotoky">DOI:10.1007/s11033-022-08193-4</ref>. The spike protein of SARS-CoV-2 enters our bodies and binds to the RBD, allowing the spike protein access to ACE2 and our host cells <ref name=”Jackson”>DOI:10.1038/s41580-021-00418-x</ref>. Once the spike protein has access to our host cells, it is able to further infect our cells and spread the virus throughout our bodies, causing us to get sick. In order to create an effective vaccine, the pathway between the spike protein and the RBD needs to be [https://www.sciencedirect.com/science/article/pii/S0166354223000190 interrupted]. | The enzyme angiotensin converting enzyme 2 (ACE2) is attached to our cell membranes bound to a receptor binding domain (RBD) <ref name="Borkotoky">DOI:10.1007/s11033-022-08193-4</ref>. The spike protein of SARS-CoV-2 enters our bodies and binds to the RBD, allowing the spike protein access to ACE2 and our host cells <ref name=”Jackson”>DOI:10.1038/s41580-021-00418-x</ref>. Once the spike protein has access to our host cells, it is able to further infect our cells and spread the virus throughout our bodies, causing us to get sick. In order to create an effective vaccine, the pathway between the spike protein and the RBD needs to be [https://www.sciencedirect.com/science/article/pii/S0166354223000190 interrupted]. | ||
| + | <scene name='10/1076049/Antibody/2'>Antibody Vaccine</scene> | ||
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| + | <scene name='10/1076049/Antibody/4'>Antibody Binding Site</scene> | ||
<scene name='10/1075216/Practice/2'>Overview Image</scene> | <scene name='10/1075216/Practice/2'>Overview Image</scene> | ||
Revision as of 19:27, 1 April 2025
=SARS CoV-2 Protein Inhibitors (AHB2 and LCB1/LCB3)=
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References
PDB Files
[1]https://www.rcsb.org/structure/7UHB
Student Contributors
- Giavanna Yowell
- Shea Bailey
- Matthew Pereira
