9uk1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of WDR5 in complex with EMBOW== | |
| - | + | <StructureSection load='9uk1' size='340' side='right'caption='[[9uk1]], [[Resolution|resolution]] 2.02Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9uk1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UK1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9uk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9uk1 OCA], [https://pdbe.org/9uk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9uk1 RCSB], [https://www.ebi.ac.uk/pdbsum/9uk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9uk1 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OSCRI_HUMAN OSCRI_HUMAN] Represses translation of the downstream SCRIB protein (PubMed:34535749). Translation of oSCRIB hinders SCRIB translation but does not completely abolish it, probably due to leaky scanning which allows the ribosome to bypass the weaker oSCRIB start codon and initiate translation at the stronger SCRIB start codon (PubMed:34535749).<ref>PMID:34535749</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen M-X]] | ||
| + | [[Category: Min J-R]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Crystal structure of WDR5 in complex with EMBOW
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