This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vpt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1vpt.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1vpt.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1vpt| PDB=1vpt | SCENE= }}
{{STRUCTURE_1vpt| PDB=1vpt | SCENE= }}
-
'''AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE'''
+
===AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE===
-
==Overview==
+
<!--
-
VP39 is a bifunctional vaccinia virus protein that acts as both an mRNA cap-specific RNA 2'-O-methyltransferase and a poly(A) polymerase processivity factor. Here, we report the 1.85 A crystal structure of a VP39 variant complexed with its AdoMet cofactor. VP39 comprises a single core domain with structural similarity to the catalytic domains of other methyltransferases. Surface features and mutagenesis data suggest two possible RNA-binding sites with novel underlying architecture, one of which forms a cleft spanning the region adjacent to the methyltransferase active site. This report provides a prototypic structure for an RNA methyltransferase, a protein that interacts with the mRNA 5' cap, and an intact poxvirus protein.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8612277}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8612277 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8612277}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Rna cap]]
[[Category: Rna cap]]
[[Category: Vaccinia]]
[[Category: Vaccinia]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:46:32 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:46:11 2008''

Revision as of 17:46, 27 July 2008

Image:1vpt.png

Template:STRUCTURE 1vpt

AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE

Template:ABSTRACT PUBMED 8612277

About this Structure

1VPT is a Single protein structure of sequence from Vaccinia virus. Full crystallographic information is available from OCA.

Reference

The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends., Hodel AE, Gershon PD, Shi X, Quiocho FA, Cell. 1996 Apr 19;85(2):247-56. PMID:8612277

Page seeded by OCA on Sun Jul 27 20:46:11 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vpt"
Personal tools