JMS/Sandbox/msn2

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# Msn2 (P33748): Interactive Structure of a Yeast Stress-Responsive Transcription Factor
# Msn2 (P33748): Interactive Structure of a Yeast Stress-Responsive Transcription Factor
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<applet load='AF-P33748-F1-model v4.pdb' size='400' frame='true' align='right' caption='' scene='10/1080095/Msn2/1'/>__NOTOC__
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<applet load='AF-P33748-F1-model_v4.pdb' size='400' frame='true' align='right' caption='Msn2 (P33748) AlphaFold Model. Click links below to explore.' scene='10/1080095/Msn2/1'/>__NOTOC__
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=== Zinc Fingers ===
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Msn2 binds DNA via two C2H2 zinc finger domains located in the C-terminal region (residues 647-665 and 676-698).[4] These domains recognize the Stress Response Element (STRE) in the promoters of target genes.[1, 45] The AlphaFold model predicts these domains with high confidence (blue regions in the default view). Click the link to highlight these domains and the coordinating Zinc ions.
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(<jmol><jmolLink>
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<script>
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select 647-665, 676-698; color magenta; backbone 0.7; wireframe 0.15;
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select zn; spacefill 1.2; color cpk;
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selectionHalos ON; delay 1.5; selectionHalos OFF;
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center selected; zoom 150;
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</script>
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<text>Highlight Zinc Fingers (DNA Binding: 647-665, 676-698)</text>
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</jmolLink></jmol>)
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Revision as of 14:15, 5 May 2025

  1. Msn2 (P33748): Interactive Structure of a Yeast Stress-Responsive Transcription Factor

Msn2 (P33748) AlphaFold Model. Click links below to explore.

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Joseph M. Steinberger

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