9o9s
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human MPC matrix-open== | |
| - | + | <StructureSection load='9o9s' size='340' side='right'caption='[[9o9s]], [[Resolution|resolution]] 3.57Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9o9s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9O9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9O9S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.57Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I2R:(~{E})-2-cyano-3-(1-phenylindol-3-yl)prop-2-enoic+acid'>I2R</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9o9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9o9s OCA], [https://pdbe.org/9o9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9o9s RCSB], [https://www.ebi.ac.uk/pdbsum/9o9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9o9s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/MPC1_HUMAN MPC1_HUMAN] Mitochondrial pyruvate carrier deficiency. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/MPC1_HUMAN MPC1_HUMAN] Mediates the uptake of pyruvate into mitochondria.<ref>PMID:22628558</ref> <ref>PMID:26253029</ref> <ref>PMID:27317664</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Qi X]] | ||
| + | [[Category: Sun Y]] | ||
| + | [[Category: Wang Y]] | ||
Current revision
Structure of human MPC matrix-open
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