1w0i

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{{STRUCTURE_1w0i| PDB=1w0i | SCENE= }}
{{STRUCTURE_1w0i| PDB=1w0i | SCENE= }}
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'''ARABIDOPSIS THALIANA MITOCHONDRIAL KAS'''
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===ARABIDOPSIS THALIANA MITOCHONDRIAL KAS===
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==Overview==
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Mitochondrial fatty acid synthesis is catalyzed by a dissociated fatty acid synthase similar to those of plant plastids and bacteria. The crystal structure of a mitochondrial beta-ketoacyl-[acyl carrier protein] synthase (mtKAS), namely that from Arabidopsis thaliana, has been determined for the first time. This enzyme accomplishes the vital condensation steps in constructing fatty acid carbon skeletons. The product profile of mtKAS is unusual in that C8 and C(14-16) fatty acyl chains predominate. An enzyme architecture that likely is the basis for the observed bimodal profile of mtKAS products can be derived from the shape of the acyl binding pocket.
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{{ABSTRACT_PUBMED_15527780}}
==About this Structure==
==About this Structure==
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[[Category: Lipid metabolism]]
[[Category: Lipid metabolism]]
[[Category: Synthase]]
[[Category: Synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:59:41 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:10:04 2008''

Revision as of 11:10, 29 July 2008

Image:1w0i.png

Template:STRUCTURE 1w0i

ARABIDOPSIS THALIANA MITOCHONDRIAL KAS

Template:ABSTRACT PUBMED 15527780

About this Structure

1W0I is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Structure of the mitochondrial beta-ketoacyl-[acyl carrier protein] synthase from Arabidopsis and its role in fatty acid synthesis., Olsen JG, Rasmussen AV, von Wettstein-Knowles P, Henriksen A, FEBS Lett. 2004 Nov 5;577(1-2):170-4. PMID:15527780

Page seeded by OCA on Tue Jul 29 14:10:04 2008

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