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9ooo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human delta 2 receptor with R710W Cerebellar Ataxia mutation in the apo closed state== | |
| - | + | <StructureSection load='9ooo' size='340' side='right'caption='[[9ooo]], [[Resolution|resolution]] 3.68Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ooo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OOO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.68Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ooo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ooo OCA], [https://pdbe.org/9ooo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ooo RCSB], [https://www.ebi.ac.uk/pdbsum/9ooo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ooo ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/GRID2_HUMAN GRID2_HUMAN] Autosomal recessive congenital cerebellar ataxia due to GRID2 deficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GRID2_HUMAN GRID2_HUMAN] Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ahmed F]] | ||
| + | [[Category: Khau J]] | ||
| + | [[Category: Mondal AK]] | ||
| + | [[Category: Twomey EC]] | ||
| + | [[Category: Wang H]] | ||
Current revision
Human delta 2 receptor with R710W Cerebellar Ataxia mutation in the apo closed state
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Categories: Homo sapiens | Large Structures | Ahmed F | Khau J | Mondal AK | Twomey EC | Wang H
