1w8b

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[[Image:1w8b.jpg|left|200px]]
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{{Seed}}
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[[Image:1w8b.png|left|200px]]
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{{STRUCTURE_1w8b| PDB=1w8b | SCENE= }}
{{STRUCTURE_1w8b| PDB=1w8b | SCENE= }}
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'''FACTOR7- 413 COMPLEX'''
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===FACTOR7- 413 COMPLEX===
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==Overview==
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We describe the structure-based design and synthesis of highly potent, orally bioavailable tissue factor/factor VIIa inhibitors which interfere with the coagulation cascade by selective inhibition of the extrinsic pathway.
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The line below this paragraph, {{ABSTRACT_PUBMED_16213138}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16213138 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16213138}}
==About this Structure==
==About this Structure==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:17:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:27:45 2008''

Revision as of 14:27, 27 July 2008

Image:1w8b.png

Template:STRUCTURE 1w8b

FACTOR7- 413 COMPLEX

Template:ABSTRACT PUBMED 16213138

About this Structure

1W8B is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors., Zbinden KG, Obst-Sander U, Hilpert K, Kuhne H, Banner DW, Bohm HJ, Stahl M, Ackermann J, Alig L, Weber L, Wessel HP, Riederer MA, Tschopp TB, Lave T, Bioorg Med Chem Lett. 2005 Dec 1;15(23):5344-52. Epub 2005 Oct 4. PMID:16213138

Page seeded by OCA on Sun Jul 27 17:27:45 2008

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