Gp41 3D Structures

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Current revision (09:54, 27 July 2025) (edit) (undo)
 
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*Gp41 from HIV-1; Domains – helix-bundle – 1-40; ectodomain – 93-165;core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854
+
*Gp41 from HIV-1; Domains – helix-bundle or coiled-coil – 1-40; ectodomain – 93-165;core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854
-
**[[2zfc]], [[3u91]] – Gp41 N-terminal residues 1-49 <br />
+
**[[2zfc]], [[3u91]] – Gp41 N-terminal residues 1-49<br />
**[[3k9a]] – Gp41 residues 1-108 (mutant)<br />
**[[3k9a]] – Gp41 residues 1-108 (mutant)<br />
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**[[1aik]], [[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]], [[1szt]], [[3vu5]], [[3vu6]] - Gp41 N-peptide domain <br />
+
**[[8f3a]], [[8f3b]] – Gp41 helix bundle <br />
-
**[[1env]], [[3cp1]], [[3cyo]], [[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]], [[5ka6]], [[5ka5]], [[4i2l]] – Gp41 N-peptide domain (mutant)<br />
+
**[[1aik]], [[1df4]], [[1df5]], [[1dlb]], [[1jpx]], [[1qr8]], [[1qr9]], [[1szt]], [[3vu5]], [[3vu6]], [[8w2y]], [[8w32]], [[8w37]], [[9arn]], [[9arp]], [[9hs7]] – Gp41 N-peptide domain<br />
 +
**[[1env]], [[1f23]], [[1i5x]], [[1i5y]], [[1k33]], [[1k34]], [[2ot5]], [[3cp1]], [[3cyo]], [[5ka6]], [[5ka5]], [[4i2l]] – Gp41 N-peptide domain (mutant)<br />
**[[5jyn]], [[6b3u]], [[6dln]], [[7loi]] – Gp41 transmembrane domain - NMR<br />
**[[5jyn]], [[6b3u]], [[6dln]], [[7loi]] – Gp41 transmembrane domain - NMR<br />
**[[2mk3]] – Gp41 ectodomain - NMR<br />
**[[2mk3]] – Gp41 ectodomain - NMR<br />
-
**[[5vwl]] – Gp41 tail domain - NMR<br />
+
**[[5vwl]] – Gp41 tail domain - NMR<br />
**[[6uju]], [[6ujv]], [[7loh]] – Gp41 transmembrane+tail domains (mutant) - NMR<br />
**[[6uju]], [[6ujv]], [[7loh]] – Gp41 transmembrane+tail domains (mutant) - NMR<br />
**[[3f4y]], [[3f4z]], [[3f50]] – Gp41 + Gp120 six-helix bundle<br />
**[[3f4y]], [[3f4z]], [[3f50]] – Gp41 + Gp120 six-helix bundle<br />
 +
**[[8duo]] – Gp41 – T4 phage - Cryo EM <br />
*Gp41 complexes
*Gp41 complexes
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**[[6v0r]], [[6vfl]], [[6vl5]], [[6vrw]], [[7l6o]], [[7l7t]], [[7l7u]], [[7sc5]], [[7ska]], [[8f7t]], [[8fad]], [[8fae]] – Gp41 core + Gp120 – Cryo EM <br />
**[[6v0r]], [[6vfl]], [[6vl5]], [[6vrw]], [[7l6o]], [[7l7t]], [[7l7u]], [[7sc5]], [[7ska]], [[8f7t]], [[8fad]], [[8fae]] – Gp41 core + Gp120 – Cryo EM <br />
**[[8tgw]] – Gp41 core (mutant) + Gp120 (mutant) – Cryo EM <br />
**[[8tgw]] – Gp41 core (mutant) + Gp120 (mutant) – Cryo EM <br />
-
**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6ck9]], [[6chb]], [[6ch9]], [[6ch8]], [[6ch7]], [[5w6d]], [[4nrx]], [[5fyk]], [[5fyj]], [[4nco]], [[6mdt]], [[6mco]], [[6vkn]], [[6wix]], [[8d0y]] – Gp41 core + Gp120 + antibody<br />
+
**[[4nco]], [[4nrx]], [[5c7k]], [[5cjx]], [[5d9q]], [[5fyj]], [[5fyk]], [[5i8h]], [[5js9]], [[5jsa]], [[5um8]], [[5utf]], [[5uty]], [[5v8l]], [[5v8m]], [[5w6d]], [[6ch7]], [[6ch8]], [[6ch9]], [[6chb]], [[6ck9]], [[6mco]], [[6mdt]],
-
**[[7l6o]] – Gp41 core + Gp120 Clade A/E (mutant) <br />
+
[[6vkn]], [[6wix]], [[8d0y]], [[8e1p]] – Gp41 core + Gp120 + antibody<br />
-
**[[3j5m]], [[6mpg]], [[6mph]], [[6n1v]], [[6n1w]], [[6x96]], [[6x97]], [[7kde]], [[7lg6]], [[7lu9]], [[7lxm]], [[7lxn]], [[7ly9]], [[7mdt]], [[7mdu]], [[7mxe]], [[7n28]], [[7rsn]], [[7rso]], [[7sd3]], [[7sq1]], [[7t73]], [[7t74]], [[7t75]], [[7t76]], [[7t77]], [[7t9a]], [[7t9b]], [[7tco]], [[7tfn]], [[7tfo]], [[7ugn]], [[7ugp]], [[7ugq]], [[7ur6]], [[7z3a]], [[7zlk]], [[8d4r]], [[8d53]], [[8dok]], [[8dow]], [[8dp1]], [[8euu]], [[8euv]], [[8f92]], [[8fis]], [[8fk5]], [[8flw]], [[8g85]], [[8g9w]], [[8g9x]], [[8g9y]], [[8gas]], [[8s2e]], [[8sal]], [[8saq]], [[8sar]], [[8sas]], [[8sat]], [[8sau]], [[8sav]], [[8sax]], [[8sb0]], [[8sb1]], [[8sb4]], [[8sb5]], [[8sw3]], [[8sw4]], [[8sw7]], [[8sww]], [[8swx]], [[8t2e]], [[8t2f]], [[8t49]], [[8t4a]], [[8t4b]], [[8t4d]], [[8t4k]], [[8t4l]], [[8tgo]], [[8tng]], [[8tnh]], [[8tni]], [[8tnu]], [[8to7]], [[8to9]], [[8top]], [[8tox]], [[8tq1]], [[8ult]], [[8ulu]], [[8vgv]], [[8vgw]], [[8vh1]], [[8vh3]], [[9aug]], [[9auh]], [[9aui]], [[9axd]], [[9axi]], [[9axk]], [[9ay6]], [[9ayv]], [[9ber]], [[9bew]], [[9bf6]], [[9bnk]], [[9bnl]], [[9bnm]], [[9bnp]], [[9bth]], [[9bti]], [[9btj]], [[9btl]], [[9btv]], [[9d1w]], [[9d3d]], [[9d7g]], [[9d7h]], [[9d7i]], [[9d7o]], [[9d7p]], [[9dmb]], [[9ehl]], [[9ehm]], [[9evz]], [[9nhh]], [[9nhi]], [[9nhj]], [[9nhk]], [[9nhl]], [[9nhm]], [[9nhn]], [[9nho]], [[9ni9]] – Gp41 core + Gp120 Clade A/E + antibody – Cryo EM<br />
+
**[[3j5m]], [[6mpg]], [[6mph]], [[6n1v]], [[6n1w]], [[6x96]], [[6x97]], [[7kde]], [[7lg6]], [[7lu9]], [[7lxm]], [[7lxn]], [[7ly9]], [[7mdt]], [[7mdu]], [[7mxe]], [[7n28]], [[7rsn]], [[7rso]], [[7sd3]], [[7sq1]], [[7t73]], [[7t74]], [[7t75]], [[7t76]], [[7t77]], [[7t9a]], [[7t9b]], [[7tco]], [[7tfn]], [[7tfo]], [[7ugn]], [[7ugp]], [[7ugq]], [[7ur6]], [[7z3a]], [[7zlk]], [[8d4r]], [[8d53]], [[8dok]], [[8dow]], [[8dp1]], [[8euu]], [[8euv]], [[8euw]], [[8f92]], [[8f9g]], [[8f9m]], [[8fis]], [[8fk5]], [[8fl1]], [[8flw]], [[8g4m]], [[8g85]], [[8g9w]], [[8g9x]], [[8g9y]], [[8gas]], [[8jtd]], [[8jtm]], [[8s2e]], [[8sal]], [[8san]], [[8saq]], [[8sar]], [[8sas]], [[8sat]], [[8sau]], [[8sav]], [[8saw]], [[8sax]], [[8say]], [[8sb0]], [[8sb1]], [[8sb2]], [[8sb3]], [[8sb4]], [[8sb5]], [[8sw3]], [[8sw4]], [[8sw7]], [[8sww]], [[8swx]], [[8t2e]], [[8t2f]], [[8t49]], [[8t4a]], [[8t4b]], [[8t4d]], [[8t4k]], [[8t4l]], [[8tgo]], [[8tng]], [[8tnh]], [[8tni]], [[8tnu]], [[8to7]], [[8to9]], [[8top]], [[8tox]], [[8tq1]], [[8ult]], [[8ulu]], [[8vfv]], [[8vgv]], [[8vgw]], [[8vh1]], [[8vh3]], [[9atz]], [[9aug]], [[9auh]], [[9aui]], [[9axd]], [[9axi]], [[9axk]], [[9ay6]], [[9ays]], [[9ayv]], [[9ber]], [[9bew]], [[9bf6]], [[9bnk]], [[9bnl]], [[9bnm]], [[9bnp]], [[9bth]], [[9bti]], [[9btj]], [[9btl]], [[9btv]], [[9d1w]], [[9d3d]], [[9d7g]], [[9d7h]], [[9d7i]], [[9d7o]], [[9d7p]], [[9d98]], [[9dmb]], [[9ehl]], [[9ehm]], [[9evz]], [[9nhh]], [[9nhi]], [[9nhj]], [[9nhk]], [[9nhl]], [[9nhm]], [[9nhn]], [[9nho]], [[9ni9]] – Gp41 core + Gp120 Clade A/E + antibody – Cryo EM<br />
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**[[6ot1]], [[6x98]], [[7uoj]], [[8fr6]], [[8g4t]], [[8gje]], [[8tkc]], [[8tl2]], [[8tl3]], [[8tl4]], [[8tr3]] – Gp41 (mutant) + Gp120 Clade A/E (mutant) + antibody – Cryo EM<br />
+
**[[6ot1]], [[6x98]], [[7uoj]], [[8fr6]], [[8g4t]], [[8gje]], [[8tkc]], [[8tl2]], [[8tl3]], [[8tl4]], [[8tl5]], [[8tr3]] – Gp41 (mutant) + Gp120 Clade A/E (mutant) + antibody – Cryo EM<br />
**[[9d90]] – Gp41 (mutant) + Gp120 (mutant) + antibody + CD4 – Cryo EM<br />
**[[9d90]] – Gp41 (mutant) + Gp120 (mutant) + antibody + CD4 – Cryo EM<br />
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**[[8czz]], [[8dto]], [[8g6u]] – Gp41 + Gp120 Clade A/E (mutant) + antibody – Cryo EM<br />
+
**[[8czz]], [[8dto]], [[8g6u]], [[8swv]] – Gp41 + Gp120 Clade A/E (mutant) + antibody – Cryo EM<br />
-
**[[6nnj]], [[6nnf]], [[6nm6]] – Gp41 core (mutant) + Gp120 + antibody<br />
+
**[[6nm6]] [[6nnf]], [[6nnj]] – Gp41 core (mutant) + Gp120 + antibody<br />
**[[6opa]], [[6vzi]], [[6w03]] – Gp41 core + Gp160 + antibody<br />
**[[6opa]], [[6vzi]], [[6w03]] – Gp41 core + Gp160 + antibody<br />
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**[[6oz4]], [[6ozc]], [[6vn0]], [[7ugo]] – Gp41 core + Gp160 + antibody – Cryo EM<br />
+
**[[6oz4]], [[6ozc]], [[6vn0]], [[7t9t]], [[7tcn]], [[7ugo]], [[8c8t]], [[8saz]], [[8sxi]], [[8sxj]], [[8tjr]], [[8ulr]], [[8uls]], [[9bio]], [[9f02]] – Gp41 core + Gp160 + antibody – Cryo EM<br />
 +
**[[8tjs]] – Gp41 core (mutant) + Gp160 + antibody – Cryo EM<br />
 +
**[[8ttw]] – Gp41 core (mutant) + Gp160 (mutant) + antibody – Cryo EM<br />
**[[7lpn]] – Gp41 core + Gp160 + VHH – Cryo EM<br />
**[[7lpn]] – Gp41 core + Gp160 + VHH – Cryo EM<br />
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**[[4cc8]], [[6cdi]], [[6orn]], [[6oo]], [[6orp]], [[6orq]], [[6okp]], [[6nqd]], [[6mn7]], [[6cuf]], [[6cue]], [[6olp]], [[6pw6]], [[6u59]], [[6uda]], [[6udk]], [[6ulc]], [[6um6]], [[6um7]], [[6v8x]], [[6v8z]], [[6vlr]], [[6vo0]], [[6vo1]], [[6vtt]], [[6vy2]], [[6nf5]], [[6nf2]], [[6nfc]], [[6oro]], [[6osy]], [[6u59]], [[6vi0]], [[6vo3]], [[6x9r]], [[6x9s]], [[6x9t]], [[6x9u]], [[6x9v]], [[6xrt]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7ll1]], [[7ll2]], [[7llk]], [[7lo6]], [[7lua]], [[7mxd]], [[7n65]], [[7pc2]], [[7rai]], [[7t74]], [[7t76]], [[7ucg]] – Gp41 core + Gp120 + antibody – Cryo EM<br />
+
**[[4cc8]], [[6cdi]], [[6cuf]], [[6cue]], [[6mn7]], [[6nf2]], [[6nf5]], [[6nfc]], [[6nqd]], [[6okp]], [[6olp]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6osy]], [[6pw6]], [[6u59]], [[6uda]], [[6udj]], [[6udk]], [[6ulc]], [[6um6]], [[6um7]], [[6v8x]], [[6v8z]], [[6vi0]], [[6vlr]], [[6vo0]], [[6vo1]], [[6vo3]], [[6vtt]], [[6vy2]], [[6x9r]], [[6x9s]], [[6x9t]], [[6x9u]], [[6x9v]], [[6xrt]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7ll1]], [[7ll2]], [[7llk]], [[7lo6]], [[7lua]], [[7mxd]], [[7n65]], [[7pc2]], [[7rai]], [[7t74]], [[7t76]], [[7ucg]] – Gp41 core + Gp120 + antibody – Cryo EM<br />
**[[4tvp]], [[6utk]], [[6v6w]], [[7kmd]], [[7ucf]], [[8d50]] – Gp41 core + Gp120 + antibody <br />
**[[4tvp]], [[6utk]], [[6v6w]], [[7kmd]], [[7ucf]], [[8d50]] – Gp41 core + Gp120 + antibody <br />
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**[[6nc3]], [[6nc2]] – Gp41 core (mutant) + Gp120 + antibody – Cryo EM<br />
+
**[[6nc2]], [[6nc3]] – Gp41 core (mutant) + Gp120 + antibody – Cryo EM<br />
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**[[5u1f]], [[5thr]] – Gp41 core + Gp120 + antibody + CD4<br />
+
**[[5thr]], [[5u1f]] – Gp41 core + Gp120 + antibody + CD4<br />
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**[[6u0l]], [[6u0n]], [[6x5b]], [[8dc5]] – Gp41 core + Gp120 + antibody + CD4 – Cryo EM<br />
+
**[[6u0l]], [[6u0n]], [[6x5b]], [[8d5c]] – Gp41 core + Gp120 + antibody + CD4 – Cryo EM<br />
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**[[6opn]], [[6x5c]] – Gp41 core + Gp160 + CD4 – Cryo EM<br />
+
**[[6opn]], [[6x5c]], [[8fyi]], [[8fyj]] – Gp41 core + Gp160 + CD4 – Cryo EM<br />
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**[[6opo]], [[6opp]], [[6opq]], [[6u0l]] – Gp41 core + Gp160 + antibody + CD4 – Cryo EM<br />
+
**[[6opo]], [[6opp]], [[6opq]] – Gp41 core + Gp160 + antibody + CD4 – Cryo EM<br />
**[[7txd]] – Gp41 core + Gp120 + darpin + CD4 – Cryo EM<br />
**[[7txd]] – Gp41 core + Gp120 + darpin + CD4 – Cryo EM<br />
**[[6um5]] – Gp41 core + Gp120 + antibody + CH848 – Cryo EM<br />
**[[6um5]] – Gp41 core + Gp120 + antibody + CH848 – Cryo EM<br />
**[[6vpx]], [[7lok]] – Gp41 core + Gp120 + antibody + peptide – Cryo EM<br />
**[[6vpx]], [[7lok]] – Gp41 core + Gp120 + antibody + peptide – Cryo EM<br />
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**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[5h0n]], [[5zpw]] – Gp41 N-peptide domain + fusion inhibitor peptide<br />
+
**[[2r3c]], [[2r5b]], [[2r5d]], [[2z2t]], [[2zzo]], [[3aha]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vie]], [[3vtp]], [[5h0n]], [[5zpw]] – Gp41 N-peptide domain + fusion inhibitor peptide<br />
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**[[5hm1]] – Gp41 core + llama antibody <br />
+
**[[5hm1]] – Gp41 core +llama antibody <br />
**[[3p30]] – Gp41 ectodomain + antibody<br />
**[[3p30]] – Gp41 ectodomain + antibody<br />
 +
**[[8vwe]] – Gp41 helix bundle + antibody<br />
**[[3o3x]] – arGp41 - artificial<br />
**[[3o3x]] – arGp41 - artificial<br />
**[[4dzu]] – arGp41 + 3-α<br />
**[[4dzu]] – arGp41 + 3-α<br />
**[[4dzv]] – arGp41 + 4-α/β<br />
**[[4dzv]] – arGp41 + 4-α/β<br />
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*Gp41 from SIV (Simian Immunodeficiency Virus)
+
*GP41 from Simian Immunodeficiency Virus
**[[2siv]] – Gp41 core<br />
**[[2siv]] – Gp41 core<br />
-
**[[2ezo]], [[2ezp]], [[2ezq]], [[2ezr]], [[2ezs]], [[1qce]] – Gp41 core - NMR<br />
+
**[[1qce]], [[2ezo]], [[2ezp]], [[2ezq]], [[2ezr]], [[2ezs]] – Gp41 core - NMR<br />
-
**[[1qbz]], [[1jq0]] – Gp41 core (mutant)<br />
+
**[[1jq0]], [[1qbz]] – Gp41 core (mutant)<br />
**[[7t2p]], [[7t4g]], [[8dua]] – Gp41 core + Gp120 + antibody – Cryo EM<br />
**[[7t2p]], [[7t4g]], [[8dua]] – Gp41 core + Gp120 + antibody – Cryo EM<br />
 +
 +
*GP41 from Pseudomonas virus
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 +
**[[8eon]], [[9b45]] – Gp41 in capsid complex – Cryo EM<br />
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}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Gp41

Updated on 27-July-2025

6vkn, 6wix, 8d0y, 8e1p – Gp41 core + Gp120 + antibody

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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