9pse
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==In situ MicroED structure of IL-5 activated human eosinophil major basic protein-1== | |
| - | + | <StructureSection load='9pse' size='340' side='right'caption='[[9pse]], [[Resolution|resolution]] 3.18Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9pse]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PSE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 3.18Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pse OCA], [https://pdbe.org/9pse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pse RCSB], [https://www.ebi.ac.uk/pdbsum/9pse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pse ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/PRG2_HUMAN PRG2_HUMAN] Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.<ref>PMID:10913121</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bingman CA]] | ||
| + | [[Category: Mitchell J]] | ||
| + | [[Category: Mosher D]] | ||
| + | [[Category: Wright ER]] | ||
| + | [[Category: Yang JE]] | ||
Current revision
In situ MicroED structure of IL-5 activated human eosinophil major basic protein-1
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