1ztl
From Proteopedia
(New page: 200px<br /> <applet load="1ztl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ztl, resolution 2.60Å" /> '''Crystal Structure o...) |
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| - | [[Image:1ztl.gif|left|200px]]<br /> | + | [[Image:1ztl.gif|left|200px]]<br /><applet load="1ztl" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1ztl" size=" | + | |
caption="1ztl, resolution 2.60Å" /> | caption="1ztl, resolution 2.60Å" /> | ||
'''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide'''<br /> | '''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1ZTL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with SO4 and 737 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] Full crystallographic information is available from [http:// | + | 1ZTL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=737:'>737</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZTL OCA]. |
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Abdel-Meguid, S | + | [[Category: Abdel-Meguid, S S.]] |
[[Category: Babine, R.]] | [[Category: Babine, R.]] | ||
[[Category: Bibbins, F.]] | [[Category: Bibbins, F.]] | ||
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[[Category: Quinn, J.]] | [[Category: Quinn, J.]] | ||
[[Category: Rynkiewicz, M.]] | [[Category: Rynkiewicz, M.]] | ||
| - | [[Category: Strickler, J | + | [[Category: Strickler, J E.]] |
[[Category: 737]] | [[Category: 737]] | ||
[[Category: SO4]] | [[Category: SO4]] | ||
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[[Category: inhibitors]] | [[Category: inhibitors]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:18:55 2008'' |
Revision as of 14:18, 21 February 2008
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide
Disease
Known diseases associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]
About this Structure
1ZTL is a Single protein structure of sequence from Homo sapiens with and as ligands. Active as Coagulation factor XIa, with EC number 3.4.21.27 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 16:18:55 2008
Categories: Coagulation factor XIa | Homo sapiens | Single protein | Abdel-Meguid, S S. | Babine, R. | Bibbins, F. | Jin, L. | Meyers, H. | Nagafuji, P. | Quinn, J. | Rynkiewicz, M. | Strickler, J E. | 737 | SO4 | Fxia | Inhibitors
