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9t3j

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Current revision (08:23, 11 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9t3j is ON HOLD
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==Protease from Norovirus Sydney GII.4 strain with crystallization epitope mutation H50Y==
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<StructureSection load='9t3j' size='340' side='right'caption='[[9t3j]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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Authors: Fairhead, M., MacLean, E.M., Ni, X., Wright, N.D., Koekemoer, L., von Delft, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9t3j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus_Sydney_2212 Norovirus Sydney 2212]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9T3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9T3J FirstGlance]. <br>
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Description: Protease from Norovirus Sydney GII.4 strain with crystallization epitope mutation H50Y
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.411&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9t3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9t3j OCA], [https://pdbe.org/9t3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9t3j RCSB], [https://www.ebi.ac.uk/pdbsum/9t3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9t3j ProSAT]</span></td></tr>
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[[Category: Von Delft, F]]
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</table>
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[[Category: Fairhead, M]]
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== Function ==
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[[Category: Maclean, E.M]]
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[https://www.uniprot.org/uniprot/A0A3Q8EAF6_9CALI A0A3Q8EAF6_9CALI] 3C-like protease processes the polyprotein: 3CLpro-RdRp is first released by autocleavage, then all other proteins are cleaved. May cleave polyadenylate-binding protein thereby inhibiting cellular translation.[PROSITE-ProRule:PRU00870]
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[[Category: Ni, X]]
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__TOC__
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[[Category: Koekemoer, L]]
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</StructureSection>
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[[Category: Wright, N.D]]
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[[Category: Large Structures]]
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[[Category: Norovirus Sydney 2212]]
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[[Category: Fairhead M]]
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[[Category: Koekemoer L]]
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[[Category: MacLean EM]]
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[[Category: Ni X]]
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[[Category: Wright ND]]
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[[Category: Von Delft F]]

Current revision

Protease from Norovirus Sydney GII.4 strain with crystallization epitope mutation H50Y

PDB ID 9t3j

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