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Mitogen-activated protein kinase 3D structures

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Current revision (11:37, 29 December 2025) (edit) (undo)
 
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*MAPK8 or JNK1
*MAPK8 or JNK1
 +
**[[8x5m]] - hMAPK8 JNK1 <br />
**[[8x5m]] - hMAPK8 JNK1 <br />
**[[2g01]], [[2gmx]], [[3o17]], [[3vud]], [[3vug]], [[3vuh]], [[3vui]], [[3vuk]], [[3vul]], [[3vum]] – hMAPK8 (mutant)+JIP1 peptide<br />
**[[2g01]], [[2gmx]], [[3o17]], [[3vud]], [[3vug]], [[3vuh]], [[3vui]], [[3vuk]], [[3vul]], [[3vum]] – hMAPK8 (mutant)+JIP1 peptide<br />
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*MAPK10 or JNK3
*MAPK10 or JNK3
 +
**[[8wgf]] – hMAPK10 catalytic domain <br />
**[[8wgf]] – hMAPK10 catalytic domain <br />
**[[1pmn]], [[1pmu]], [[1pmv]], [[2b1p]], [[2exc]], [[2o0u]], [[2o2u]], [[2ok1]], [[2p33]], [[2r9s]], [[2waj]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[3da6]], [[3fi2]], [[3fi3]], [[3fv8]], [[3g90]], [[3g9l]], [[3g9n]], [[3kvx]], [[3oy1]], [[3rtp]], [[3tti]], [[3ttj]], [[3v6r]], [[3v6s]], [[4kkh]], [[4u79]], [[4whz]], [[4x21]], [[4y46]], [[4y5h]], [[4z9l]], [[6ekd]], [[6emh]], [[7ksi]], [[7ksj]], [[7ksk]], [[7ore]], [[7orf]], [[7s1n]], [[8bzp]], [[8elc]], [[8vnx]], [[8vo4]], [[8vs0]], [[8vtf]] – hMAPK10 catalytic domain + inhibitor<br />
**[[1pmn]], [[1pmu]], [[1pmv]], [[2b1p]], [[2exc]], [[2o0u]], [[2o2u]], [[2ok1]], [[2p33]], [[2r9s]], [[2waj]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[3da6]], [[3fi2]], [[3fi3]], [[3fv8]], [[3g90]], [[3g9l]], [[3g9n]], [[3kvx]], [[3oy1]], [[3rtp]], [[3tti]], [[3ttj]], [[3v6r]], [[3v6s]], [[4kkh]], [[4u79]], [[4whz]], [[4x21]], [[4y46]], [[4y5h]], [[4z9l]], [[6ekd]], [[6emh]], [[7ksi]], [[7ksj]], [[7ksk]], [[7ore]], [[7orf]], [[7s1n]], [[8bzp]], [[8elc]], [[8vnx]], [[8vo4]], [[8vs0]], [[8vtf]] – hMAPK10 catalytic domain + inhibitor<br />
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*MAPK14 or p38 alpha
*MAPK14 or p38 alpha
 +
**[[1cm8]], [[1r39]], [[1wbo]], [[1wfc]], [[2npq]], [[3hvc]], [[3mgy]], [[3mh0]], [[3mh1]], [[3mh2]], [[3mh3]], [[3npq]], [[5etc]], [[5eti]], [[5uoj]], [[9cj2]] – hMAPK14<br />
**[[1cm8]], [[1r39]], [[1wbo]], [[1wfc]], [[2npq]], [[3hvc]], [[3mgy]], [[3mh0]], [[3mh1]], [[3mh2]], [[3mh3]], [[3npq]], [[5etc]], [[5eti]], [[5uoj]], [[9cj2]] – hMAPK14<br />
**[[2lgc]] – hMAPK14 – NMR<br />
**[[2lgc]] – hMAPK14 – NMR<br />
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**[[4e6a]], [[4e6c]], [[4e8a]] - hMAPK14+ lipid<br />
**[[4e6a]], [[4e6c]], [[4e8a]] - hMAPK14+ lipid<br />
**[[8a8m]] – hMAPK14 (mutant) + dual specificity MAP2K – Cryo EM<br />
**[[8a8m]] – hMAPK14 (mutant) + dual specificity MAP2K – Cryo EM<br />
-
*[[2y8o]] – hMAPK14 (mutant) + dual specificity MAP2K peptide<br />
+
**[[2y8o]] – hMAPK14 (mutant) + dual specificity MAP2K peptide<br />
**[[4ka3]], [[4loo]], [[4lop]], [[4loq]] – hMAPK14 + docking peptide<br />
**[[4ka3]], [[4loo]], [[4lop]], [[4loq]] – hMAPK14 + docking peptide<br />
**[[8yp8]] – hMAPK14 + Tyr-protein phosphatase non-receptor peptide<br />
**[[8yp8]] – hMAPK14 + Tyr-protein phosphatase non-receptor peptide<br />

Current revision

3D Structures of Mitogen-activated protein kinase

Updated on 29-December-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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