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Template:STRUCTURE 1x70
From Proteopedia
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| - | {{ | + | {{StructureD |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1x70, resolution 2.10Å (<scene name='initialview01'>initial scene</scene>) | + | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1x70, resolution 2.10Å (<scene name='initialview01'>initial scene</scene>)}}} |
| - | + | |LIGAND= <scene name='pdbligand=715:(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE'>715</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:SUGAR+(N-ACETYL-D-GLUCOSAMINE)'>NAG</scene> | |
| - | |LIGAND= <scene name='pdbligand=715:(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE'>715</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG | + | |
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span> | ||
|GENE= DPP4, ADCP2, CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= DPP4, ADCP2, CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00326 Peptidase_S9], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00930 DPPIV_N]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00326 Peptidase_S9], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00930 DPPIV_N]</span> | ||
| - | | | + | |NONSTDRES=<scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene> |
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x70 OCA], [http://www.ebi.ac.uk/pdbsum/1x70 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1x70 RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x70 OCA], [http://www.ebi.ac.uk/pdbsum/1x70 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1x70 RCSB]</span> | ||
| + | |FUNCTION={{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004274 | text = dipeptidyl-peptidase IV activity}}{{GO|id=GO:0004287 | text = prolyl oligopeptidase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0004177 | text = aminopeptidase activity}}{{GO|id=GO:0008236 | text = serine-type peptidase activity}}{{GO|id=GO:0004252 | text = serine-type endopeptidase activity}} | ||
| + | |PROCESS={{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0006955 | text = immune response}} | ||
| + | |COMPONENT={{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0016021 | text = integral to membrane}} | ||
| + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70A01 1X70A01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70A02 1X70A02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70B01 1X70B01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70B02 1X70B02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002471 Ipr002471], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001375 Ipr001375], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002469 Ipr002469]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00326 PF00326], [http://pfam.sanger.ac.uk/family?acc=PF00930 PF00930]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P27487 P27487]</span> | ||
| + | |FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P27487 P27487]</span> | ||
}} | }} | ||
