This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1xdx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1xdx.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1xdx.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1xdx| PDB=1xdx | SCENE= }}
{{STRUCTURE_1xdx| PDB=1xdx | SCENE= }}
-
'''Solution Structure of the Tctex1 Light Chain From Chlamydomonas Inner Dynein Arm I1'''
+
===Solution Structure of the Tctex1 Light Chain From Chlamydomonas Inner Dynein Arm I1===
-
==Overview==
+
<!--
-
Tctex1 is a light chain found in both cytoplasmic and flagellar dyneins and is involved in many fundamental cellular activities, including rhodopsin transport within photoreceptors, and may function in the non-Mendelian transmission of t haplotypes in mice. Here, we present the NMR solution structure for the Tctex1 dimer from Chlamydomonas axonemal inner dynein arm I1. Structural comparisons reveal a strong similarity with the LC8 dynein light chain dimer, including formation of a strand-switched beta sheet interface. Analysis of the Tctex1 structure enables the dynein intermediate chain binding site to be identified and suggests a mechanism by which cargo proteins might be attached to this microtubule motor complex. Comparison with the alternate dynein light chain rp3 reveals how the specificity of dynein-cargo interactions mediated by these dynein components is achieved. In addition, this structure provides insight into the consequences of the mutations found in the t haplotype forms of this protein.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15698565}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15698565 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15698565}}
==About this Structure==
==About this Structure==
-
1XDX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XDX OCA].
+
1XDX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XDX OCA].
==Reference==
==Reference==
Line 29: Line 33:
[[Category: Nmr solution structure]]
[[Category: Nmr solution structure]]
[[Category: Tctex1 dimer]]
[[Category: Tctex1 dimer]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 14:54:18 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:11:12 2008''

Revision as of 03:11, 28 July 2008

Image:1xdx.png

Template:STRUCTURE 1xdx

Solution Structure of the Tctex1 Light Chain From Chlamydomonas Inner Dynein Arm I1

Template:ABSTRACT PUBMED 15698565

About this Structure

1XDX is a Single protein structure of sequence from Chlamydomonas reinhardtii. Full experimental information is available from OCA.

Reference

Solution structure of the Tctex1 dimer reveals a mechanism for dynein-cargo interactions., Wu H, Maciejewski MW, Takebe S, King SM, Structure. 2005 Feb;13(2):213-23. PMID:15698565

Page seeded by OCA on Mon Jul 28 06:11:12 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xdx"
Personal tools