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1xok

From Proteopedia

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[[Image:1xok.gif|left|200px]]
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{{STRUCTURE_1xok| PDB=1xok | SCENE= }}
{{STRUCTURE_1xok| PDB=1xok | SCENE= }}
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'''crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide'''
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===crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide===
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==Overview==
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Alfalfa mosaic virus genomic RNAs are infectious only when the viral coat protein binds to the RNA 3' termini. The crystal structure of an alfalfa mosaic virus RNA-peptide complex reveals that conserved AUGC repeats and Pro-Thr-x-Arg-Ser-x-x-Tyr coat protein amino acids cofold upon interacting. Alternating AUGC residues have opposite orientation, and they base pair in different adjacent duplexes. Localized RNA backbone reversals stabilized by arginine-guanine interactions place the adenosines and guanines in reverse order in the duplex. The results suggest that a uniform, organized 3' conformation, similar to that found on viral RNAs with transfer RNA-like ends, may be essential for replication.
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(as it appears on PubMed at http://www.pubmed.gov), where 15604410 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15604410}}
==About this Structure==
==About this Structure==
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[[Category: Atypical rna duplex]]
[[Category: Atypical rna duplex]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:17:56 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:52:42 2008''

Revision as of 14:52, 28 July 2008

Image:1xok.png

Template:STRUCTURE 1xok

crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide

Template:ABSTRACT PUBMED 15604410

About this Structure

1XOK is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication., Guogas LM, Filman DJ, Hogle JM, Gehrke L, Science. 2004 Dec 17;306(5704):2108-11. PMID:15604410

Page seeded by OCA on Mon Jul 28 17:52:42 2008

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