1xt6

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[[Image:1xt6.gif|left|200px]]
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{{STRUCTURE_1xt6| PDB=1xt6 | SCENE= }}
{{STRUCTURE_1xt6| PDB=1xt6 | SCENE= }}
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'''S35C Flavodoxin Mutant in the semiquinone state'''
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===S35C Flavodoxin Mutant in the semiquinone state===
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==Overview==
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The crystallographic structure of an engineered flavodoxin mutant from Desulfovibrio vulgaris has been analysed. Site-directed mutagenesis was used to substitute serine 35 with a cysteine to provide a possible covalent linkage. The crystal structure of the semiquinone form of this mutant is similar to the corresponding oxidation state of the wild-type flavodoxin. Analysis of the structural changes reveals the interaction between N(5)H of the flavin and the carbonyl O atom of Gly61 to be critical for modulation of the electrochemical properties of the protein.
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(as it appears on PubMed at http://www.pubmed.gov), where 15805604 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15805604}}
==About this Structure==
==About this Structure==
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[[Category: Protein]]
[[Category: Protein]]
[[Category: S35c]]
[[Category: S35c]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:28:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:45:25 2008''

Revision as of 06:45, 28 July 2008

Image:1xt6.png

Template:STRUCTURE 1xt6

S35C Flavodoxin Mutant in the semiquinone state

Template:ABSTRACT PUBMED 15805604

About this Structure

1XT6 is a Single protein structure of sequence from Desulfovibrio vulgaris. Full crystallographic information is available from OCA.

Reference

Structure of S35C flavodoxin mutant from Desulfovibrio vulgaris in the semiquinone state., Artali R, Marchini N, Meneghetti F, Cavazzini D, Cassetta A, Sassone C, Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):481-4. Epub 2005, Mar 24. PMID:15805604

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