We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1y69

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1y69.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1y69.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1y69| PDB=1y69 | SCENE= }}
{{STRUCTURE_1y69| PDB=1y69 | SCENE= }}
-
'''RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans'''
+
===RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans===
-
==Overview==
+
<!--
-
This study presents the crystal structure of domain I of the Escherichia coli ribosome recycling factor (RRF) bound to the Deinococcus radiodurans 50S subunit. The orientation of RRF is consistent with the position determined on a 70S-RRF complex by cryoelectron microscopy (cryo-EM). Alignment, however, requires a rotation of 7 degrees and a shift of the cryo-EM RRF by a complete turn of an alpha-helix, redefining the contacts established with ribosomal components. At 3.3 A resolution, RRF is seen to interact exclusively with ribosomal elements associated with tRNA binding and/or translocation. Furthermore, these results now provide a high-resolution structural description of the conformational changes that were suspected to occur on the 70S-RRF complex, which has implications for the synergistic action of RRF with elongation factor G (EF-G). Specifically, the tip of the universal bridge element H69 is shifted by 20 A toward h44 of the 30S subunit, suggesting that RRF primes the intersubunit bridge B2a for the action of EF-G. Collectively, our data enable a model to be proposed for the dual action of EF-G and RRF during ribosome recycling.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15616575}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15616575 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15616575}}
==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Ribosome]]
[[Category: Ribosome]]
[[Category: Rrf]]
[[Category: Rrf]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:55:19 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:39:30 2008''

Revision as of 01:39, 28 July 2008

Image:1y69.png

Template:STRUCTURE 1y69

RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans

Template:ABSTRACT PUBMED 15616575

About this Structure

1Y69 is a Protein complex structure of sequences from Deinococcus radiodurans. Full crystallographic information is available from OCA.

Reference

X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit., Wilson DN, Schluenzen F, Harms JM, Yoshida T, Ohkubo T, Albrecht R, Buerger J, Kobayashi Y, Fucini P, EMBO J. 2005 Jan 26;24(2):251-60. Epub 2004 Dec 23. PMID:15616575

Page seeded by OCA on Mon Jul 28 04:39:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1y69"
Personal tools