1y8b

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[[Image:1y8b.gif|left|200px]]
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{{Seed}}
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[[Image:1y8b.png|left|200px]]
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{{STRUCTURE_1y8b| PDB=1y8b | SCENE= }}
{{STRUCTURE_1y8b| PDB=1y8b | SCENE= }}
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'''Solution NMR-Derived Global Fold of Malate Synthase G from E.coli'''
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===Solution NMR-Derived Global Fold of Malate Synthase G from E.coli===
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==Overview==
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The size of proteins that can be studied by solution NMR spectroscopy has increased significantly because of recent developments in methodology. Important experiments include those that make use of approaches that increase the lifetimes of NMR signals or that define the orientation of internuclear bond vectors with respect to a common molecular frame. The advances in NMR techniques are strongly coupled to isotope labeling methods that increase sensitivity and reduce the complexity of NMR spectra. We show that these developments can be exploited in structural studies of high-molecular-weight, single-polypeptide proteins, and we present the solution global fold of the monomeric 723-residue (82-kDa) enzyme malate synthase G from Escherichia coli, which has been extensively characterized by NMR in the past several years.
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The line below this paragraph, {{ABSTRACT_PUBMED_15637152}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15637152 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15637152}}
==About this Structure==
==About this Structure==
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1Y8B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y8B OCA].
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1Y8B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y8B OCA].
==Reference==
==Reference==
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[[Category: Apo-malate synthase g]]
[[Category: Apo-malate synthase g]]
[[Category: Nmr global fold]]
[[Category: Nmr global fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:59:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:51:15 2008''

Revision as of 17:51, 27 July 2008

Image:1y8b.png

Template:STRUCTURE 1y8b

Solution NMR-Derived Global Fold of Malate Synthase G from E.coli

Template:ABSTRACT PUBMED 15637152

About this Structure

1Y8B is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

Solution NMR-derived global fold of a monomeric 82-kDa enzyme., Tugarinov V, Choy WY, Orekhov VY, Kay LE, Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):622-7. Epub 2005 Jan 6. PMID:15637152

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