1ycd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ycd.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1ycd.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ycd| PDB=1ycd | SCENE= }}
{{STRUCTURE_1ycd| PDB=1ycd | SCENE= }}
-
'''Crystal structure of yeast FSH1/YHR049W, a member of the serine hydrolase family'''
+
===Crystal structure of yeast FSH1/YHR049W, a member of the serine hydrolase family===
-
==Overview==
+
<!--
-
Yhr049w/FSH1 was recently identified in a combined computational and experimental proteomics analysis for the detection of active serine hydrolases in yeast. This analysis suggested that FSH1 might be a serine-type hydrolase belonging to the broad functional alphabeta-hydrolase superfamily. In order to get insight into the molecular function of this gene, it was targeted in our yeast structural genomics project. The crystal structure of the protein confirms that it contains a Ser/His/Asp catalytic triad that is part of a minimal alpha/beta-hydrolase fold. The architecture of the putative active site and analogies with other protein structures suggest that FSH1 may be an esterase. This finding was further strengthened by the unexpected presence of a compound covalently bound to the catalytic serine in the active site. Apparently, the enzyme was trapped with a reactive compound during the purification process.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15802654}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15802654 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15802654}}
==About this Structure==
==About this Structure==
Line 36: Line 40:
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Ysg]]
[[Category: Ysg]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 16:08:55 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:04:08 2008''

Revision as of 14:04, 27 July 2008

Image:1ycd.png

Template:STRUCTURE 1ycd

Crystal structure of yeast FSH1/YHR049W, a member of the serine hydrolase family

Template:ABSTRACT PUBMED 15802654

About this Structure

1YCD is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family., Quevillon-Cheruel S, Leulliot N, Graille M, Hervouet N, Coste F, Benedetti H, Zelwer C, Janin J, Van Tilbeurgh H, Protein Sci. 2005 May;14(5):1350-6. Epub 2005 Mar 31. PMID:15802654

Page seeded by OCA on Sun Jul 27 17:04:08 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ycd"
Personal tools