1yfn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1yfn.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1yfn.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1yfn| PDB=1yfn | SCENE= }}
{{STRUCTURE_1yfn| PDB=1yfn | SCENE= }}
-
'''Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex'''
+
===Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex===
-
==Overview==
+
<!--
-
Energy-dependent proteases often rely on adaptor proteins to modulate substrate recognition. The SspB adaptor binds peptide sequences in the stress-response regulator RseA and in ssrA-tagged proteins and delivers these molecules to the AAA+ ClpXP protease for degradation. The structure of SspB bound to an ssrA peptide is known. Here, we report the crystal structure of a complex between SspB and its recognition peptide in RseA. Notably, the RseA sequence is positioned in the peptide-binding groove of SspB in a direction opposite to the ssrA peptide, the two peptides share only one common interaction with the adaptor, and the RseA interaction site is substantially larger than the overlapping ssrA site. This marked diversity in SspB recognition of different target proteins indicates that it is capable of highly flexible and dynamic substrate delivery.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15880122}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15880122 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15880122}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Rsea]]
[[Category: Rsea]]
[[Category: Sspb]]
[[Category: Sspb]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 16:15:44 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:48:30 2008''

Revision as of 05:48, 28 July 2008

Image:1yfn.png

Template:STRUCTURE 1yfn

Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex

Template:ABSTRACT PUBMED 15880122

About this Structure

1YFN is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Versatile modes of peptide recognition by the AAA+ adaptor protein SspB., Levchenko I, Grant RA, Flynn JM, Sauer RT, Baker TA, Nat Struct Mol Biol. 2005 Jun;12(6):520-5. Epub 2005 May 8. PMID:15880122

Page seeded by OCA on Mon Jul 28 08:48:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1yfn"
Personal tools