1yia

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{{STRUCTURE_1yia| PDB=1yia | SCENE= }}
{{STRUCTURE_1yia| PDB=1yia | SCENE= }}
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'''Crystal structure of tryptophanyl tRNA synthetase II from Deinococcus radiodurans in complex with 5-Hydroxy tryptophan.'''
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===Crystal structure of tryptophanyl tRNA synthetase II from Deinococcus radiodurans in complex with 5-Hydroxy tryptophan.===
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==Overview==
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The most divergent of two tryptophanyl tRNA synthetases (TrpRS II) found in Deinococcus radiodurans interacts with a nitric oxide synthase protein that produces 4-nitro-tryptophan (4-NRP). TrpRS II efficiently charges transfer RNA(Trp) with 4-NRP and 5-hydroxy-tryptophan (5-HRP). The crystal structures of TrpRS II bound to tryptophan and 5-HRP reveal residue substitutions that accommodate modified indoles. A class of auxiliary bacterial TrpRSs conserve this capacity to charge tRNA with nonstandard amino acids.
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(as it appears on PubMed at http://www.pubmed.gov), where 15723076 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15723076}}
==About this Structure==
==About this Structure==
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[[Category: 5 hydroxy tryptophan]]
[[Category: 5 hydroxy tryptophan]]
[[Category: Trna synthetase]]
[[Category: Trna synthetase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 16:21:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:54:13 2008''

Revision as of 09:54, 29 July 2008

Image:1yia.png

Template:STRUCTURE 1yia

Crystal structure of tryptophanyl tRNA synthetase II from Deinococcus radiodurans in complex with 5-Hydroxy tryptophan.

Template:ABSTRACT PUBMED 15723076

About this Structure

1YIA is a Single protein structure of sequence from Deinococcus radiodurans r1. Full crystallographic information is available from OCA.

Reference

Structure and activity of an aminoacyl-tRNA synthetase that charges tRNA with nitro-tryptophan., Buddha MR, Crane BR, Nat Struct Mol Biol. 2005 Mar;12(3):274-5. Epub 2005 Feb 20. PMID:15723076

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