1z0r

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{{STRUCTURE_1z0r| PDB=1z0r | SCENE= }}
{{STRUCTURE_1z0r| PDB=1z0r | SCENE= }}
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'''Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transcription-State Regulator AbrB'''
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===Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transcription-State Regulator AbrB===
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==Overview==
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New relationships found in the process of updating the structural classification of proteins (SCOP) database resulted in the revision of the structure of the N-terminal, DNA-binding domain of the transition state regulator AbrB. The dimeric AbrB domain shares a common fold with the addiction antidote MazE and the subunit of uncharacterized protein MraZ implicated in cell division and cell envelope formation. It has a detectable sequence similarity to both MazE and MraZ thus providing an evolutionary link between the two proteins. The putative DNA-binding site of AbrB is found on the same face as the DNA-binding site of MazE and appears similar, both in structure and sequence, to the exposed conserved region of MraZ. This strongly suggests that MraZ also binds DNA and allows for a consensus model of DNA recognition by the members of this novel protein superfamily.
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The line below this paragraph, {{ABSTRACT_PUBMED_16223496}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16223496 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16223496}}
==About this Structure==
==About this Structure==
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1Z0R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekt 1ekt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0R OCA].
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1Z0R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekt 1ekt]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0R OCA].
==Reference==
==Reference==
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[[Category: Scop database]]
[[Category: Scop database]]
[[Category: Transition state regulator]]
[[Category: Transition state regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:02:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:11:56 2008''

Revision as of 17:12, 27 July 2008

Image:1z0r.png

Template:STRUCTURE 1z0r

Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transcription-State Regulator AbrB

Template:ABSTRACT PUBMED 16223496

About this Structure

1Z0R is a Single protein structure of sequence from Bacillus subtilis. This structure supersedes the now removed PDB entry 1ekt. Full experimental information is available from OCA.

Reference

Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins., Bobay BG, Andreeva A, Mueller GA, Cavanagh J, Murzin AG, FEBS Lett. 2005 Oct 24;579(25):5669-74. Epub 2005 Oct 4. PMID:16223496

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