1z7k

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{{STRUCTURE_1z7k| PDB=1z7k | SCENE= }}
{{STRUCTURE_1z7k| PDB=1z7k | SCENE= }}
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'''Crystal Structure of Trypsin- Ovomucoid turkey egg white inhibitor complex'''
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===Crystal Structure of Trypsin- Ovomucoid turkey egg white inhibitor complex===
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==Overview==
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Crystal structure of the complex between porcine beta-trypsin and the second domain of the Kazal-type ovomucoid turkey egg white trypsin inhibitor (OMTKY2) has been determined at 1.9A resolution. A peptide fragment from the first domain has been crystallized with the complex. Restrained-refinement of the structure led to an R-factor of 0.19 for the 32206 reflections. OMTKY2 exhibits the canonical Kazal-type fold with a central alpha-helix and a short two-stranded anti-parallel beta-sheet. The carbonyl carbon of the reactive site prefers trigonal geometry. The reactive site loop geometry of the inhibitor is complementary to the surface and charge of the binding site in beta-trypsin.
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(as it appears on PubMed at http://www.pubmed.gov), where 14672690 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14672690}}
==About this Structure==
==About this Structure==
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[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:16:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:31:31 2008''

Revision as of 07:31, 28 July 2008

Image:1z7k.png

Template:STRUCTURE 1z7k

Crystal Structure of Trypsin- Ovomucoid turkey egg white inhibitor complex

Template:ABSTRACT PUBMED 14672690

About this Structure

1Z7K is a Protein complex structure of sequences from Meleagris gallopavo and Sus scrofa. This structure supersedes the now removed PDB entry 1r0t. Full crystallographic information is available from OCA.

Reference

Crystal structure of trypsin-turkey egg white inhibitor complex., Ibrahim BS, Pattabhi V, Biochem Biophys Res Commun. 2004 Jan 2;313(1):8-16. PMID:14672690

Page seeded by OCA on Mon Jul 28 10:31:31 2008

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