This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1zax

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1zax.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1zax.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1zax| PDB=1zax | SCENE= }}
{{STRUCTURE_1zax| PDB=1zax | SCENE= }}
-
'''Ribosomal Protein L10-L12(NTD) Complex, Space Group P212121, Form B'''
+
===Ribosomal Protein L10-L12(NTD) Complex, Space Group P212121, Form B===
-
==Overview==
+
<!--
-
The L7/12 stalk of the large subunit of bacterial ribosomes encompasses protein L10 and multiple copies of L7/12. We present crystal structures of Thermotoga maritima L10 in complex with three L7/12 N-terminal-domain dimers, refine the structure of an archaeal L10E N-terminal domain on the 50S subunit, and identify these elements in cryo-electron-microscopic reconstructions of Escherichia coli ribosomes. The mobile C-terminal helix alpha8 of L10 carries three L7/12 dimers in T. maritima and two in E. coli, in concordance with the different length of helix alpha8 of L10 in these organisms. The stalk is organized into three elements (stalk base, L10 helix alpha8-L7/12 N-terminal-domain complex, and L7/12 C-terminal domains) linked by flexible connections. Highly mobile L7/12 C-terminal domains promote recruitment of translation factors to the ribosome and stimulate GTP hydrolysis by the ribosome bound factors through stabilization of their active GTPase conformation.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15989950}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15989950 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15989950}}
==About this Structure==
==About this Structure==
Line 42: Line 46:
[[Category: Translation factor recruitment]]
[[Category: Translation factor recruitment]]
[[Category: X-ray crystallography]]
[[Category: X-ray crystallography]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:24:12 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:54:32 2008''

Revision as of 02:54, 28 July 2008

Image:1zax.png

Template:STRUCTURE 1zax

Ribosomal Protein L10-L12(NTD) Complex, Space Group P212121, Form B

Template:ABSTRACT PUBMED 15989950

About this Structure

1ZAX is a Protein complex structure of sequences from Thermotoga maritima. Full crystallographic information is available from OCA.

Reference

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation., Diaconu M, Kothe U, Schlunzen F, Fischer N, Harms JM, Tonevitsky AG, Stark H, Rodnina MV, Wahl MC, Cell. 2005 Jul 1;121(7):991-1004. PMID:15989950

Page seeded by OCA on Mon Jul 28 05:54:32 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1zax"
Personal tools