2bmm
From Proteopedia
(New page: 200px<br /> <applet load="2bmm" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bmm, resolution 2.48Å" /> '''X-RAY STRUCTURE OF ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2BMM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]] with ACT and HEM as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BMM OCA]]. | + | 2BMM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]] with ACT and HEM as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BMM OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: thermostable protein]] | [[Category: thermostable protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:06:25 2007'' |
Revision as of 10:01, 30 October 2007
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X-RAY STRUCTURE OF A NOVEL THERMOSTABLE HEMOGLOBIN FROM THE ACTINOBACTERIUM THERMOBIFIDA FUSCA
Overview
The gene coding for a hemoglobin-like protein (Tf-trHb) has been, identified in the thermophilic actinobacterium Thermobifida fusca and, cloned in Escherichia coli for overexpression. The crystal structure of, the ferric, acetate-bound derivative, was obtained at 2.48 A resolution., The three-dimensional structure of Tf-trHb is similar to structures, reported for the truncated hemoglobins from Mycobacterium tuberculosis and, Bacillus subtilis in its central domain. The complete lack of diffraction, patterns relative to the N- and C-terminal segments indicates that these, are unstructured polypeptides chains, consistent with their facile, cleavage in solution. The absence of internal cavities and the presence of, two water molecules between the bound acetate ion and the protein surface, ... [(full description)]
About this Structure
2BMM is a [Single protein] structure of sequence from [Thermobifida fusca] with ACT and HEM as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
A novel thermostable hemoglobin from the actinobacterium Thermobifida fusca., Bonamore A, Ilari A, Giangiacomo L, Bellelli A, Morea V, Boffi A, FEBS J. 2005 Aug;272(16):4189-201. PMID:16098200
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